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- (rev. 3)
- Ji-hye Lee
Miniature Inverted-Repeat Transposable elements (MITEs) #
MITEs are class II non-autonomous transposable elments characterized by relatively small size (<800 bp), AT-rich sequences, and flanking terminal inverted repeats (TIRs) ranging from 10 to 200 bp.
MITEs were first identified in the maize genome and later in various other plant and animal genomes.
Insertion of a MITE can produce Target site duplication (TSD) ranging from 2 to 11 bp depending on the MITE superfamily involved.
Different MITE families are classified based upon TSD length, structure, and sequence similarity to the putative transposase of the corresponding DNA transposon.
MITEs comprise two major families, namely Stowaway-like (with TA as the TSD) and Tourist-like (with TAA as the TSD), as well as several other minor families including hAT-like (with 5, 6, or 8 bp TSDs), MULE (with 9–10 bp TSDs), and En/Spm (3-bp TSDs).
MITE mining tools #
- MITE Hunter
- MITE digger