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2회 업데이트 됨.

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  • 최초 작성자
    Kesavan
  • 최근 업데이트
    Ji-hye Lee

Structured data

Category
Biology

Miniature Inverted-Repeat Transposable elements (MITEs) #

  • MITEs are class II non-autonomous transposable elments characterized by relatively small size (<800 bp), AT-rich sequences, and flanking terminal inverted repeats (TIRs) ranging from 10 to 200 bp.

  • MITEs were first identified in the maize genome and later in various other plant and animal genomes.

  • Insertion of a MITE can produce Target site duplication (TSD) ranging from 2 to 11 bp depending on the MITE superfamily involved.

  • Different MITE families are classified based upon TSD length, structure, and sequence similarity to the putative transposase of the corresponding DNA transposon.

  • MITEs comprise two major families, namely Stowaway-like (with TA as the TSD) and Tourist-like (with TAA as the TSD), as well as several other minor families including hAT-like (with 5, 6, or 8 bp TSDs), MULE (with 9–10 bp TSDs), and En/Spm (3-bp TSDs).

MITE mining tools #

  • FINDMITE
  • MUST
  • MITE Hunter
  • RSBP
  • MITE digger
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