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Linkage map #
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Biology

linkage map 이란 #

A linkage map is a genetic map of a species or experimental population that shows the position of its known genes or genetic markers relative to each other in terms of recombination frequency, rather than a specific physical distance along each chromosome. Construction of a genetic linkage maps for any species is an important task in order to facilitate quantitative trait locus (QTL) analysis and the development of tools for marker-assisted breeding. In addition, linkage map is used to understand the genetics basis of disease. Linkage maps are not only involved in agriculture and medicine but also involved in evolutionary studies.

genetic linkage map construction 도구들 #

  1. JoinMap - BC1, F2, RIL, F1-derived and F2-derived DH, Out breeder full-sib family.

  2. Mapchart- produces charts of genetic linkage maps and QTL data. These charts are composed of a sequence of vertical bars representing the linkage groups or chromosomes.

  3. MapDisto - segregating populations like backcross, F2, doubled haploids, single-seed descent, highly recombinant lines.

  4. MapMaker - DOS/Command line interface' based tool.

  5. MSTmap - Can handle various mapping populations including BC1, DH, Hap, and RIL also able to analyze thousands of markers in a short time.

  6. QTL IciMapping - used for linkage analysis, map construction, and QTL mapping in most biparental populations.

  7. R/ASMap - uses an R/qtl format.

  8. R (프로그래밍 언어)/qtl - estimating genetic maps, identifying genotyping errors, and performing single-QTL genome scans.

  9. OneMap (Link) - Software for constructing genetic maps in experimental crosses: full-sib, RILs, F2 and backcrosses

  10. SimpleMap – uses PERL language.

  11. WinQTL cart – Maps QTLs of cross populations from inbred lines.

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